Combination of ALDH2 and ADH1B polymorphisms is associated with smoking initiation: A large-scale cross-sectional study in a Japanese population.
Sign Up to like & getrecommendations! Published in 2017 at "Drug and alcohol dependence"
DOI: 10.1016/j.drugalcdep.2016.12.015
Abstract: BACKGROUND Aldehyde dehydrogenase 2 (ALDH2; rs671, Glu504Lys) and alcohol dehydrogenase 1B (ADH1B; rs1229984, His47Arg) polymorphisms are known to strongly influence alcohol　drinking behavior. Given evidence of an association between smoking and drinking behaviors, we hypothesized that… read more here.
Keywords: aldh2 adh1b; smoking initiation; glu; adh1b polymorphisms ... See more keywords
Longitudinal effects and environmental moderation of ALDH2 and ADH1B gene variants on substance use from age 14 to 40
Sign Up to like & getrecommendations! Published in 2022 at "Development and Psychopathology"
DOI: 10.1017/s0954579422000712
Abstract: Abstract Alcohol use and dependence are strongly affected by variation in aldehyde dehydrogenase (ALDH2) and, to a lesser extent, alcohol dehydrogenase (ADH1B) genes. We use this genetic variation with an adoption design to test the… read more here.
Keywords: age; aldh2 adh1b; alcohol use; longitudinal effects ... See more keywords