SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant
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DOI: 10.1126/scitranslmed.abp9952
Abstract: The common aldehyde dehydrogenase 2 (ALDH2) alcohol flushing variant known as ALDH2*2 affects ∼8% of the world’s population. Even in heterozygous carriers, this missense variant leads to a severe loss of ALDH2 enzymatic activity and… read more here.
Keywords: cad; aldh2; dysfunction; aldh2 alcohol ... See more keywords