Lack of impact of the ALDH2 rs671 variant on breast cancer development in Japanese BRCA1/2‐mutation carriers
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5430
Abstract: The aldehyde degrading function of the ALDH2 enzyme is impaired by Glu504Lys polymorphisms (rs671, termed A allele), which causes alcohol flushing in east Asians, and elevates the risk of esophageal cancer among habitual drinkers. Recent… read more here.
Keywords: brca1; development; breast; aldh2 rs671 ... See more keywords
Alcohol metabolism genes and risks of site‐specific cancers in Chinese adults: An 11‐year prospective study
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DOI: 10.1002/ijc.33917
Abstract: Two genetic variants that alter alcohol metabolism, ALDH2‐rs671 and ADH1B‐rs1229984, can modify oesophageal cancer risk associated with alcohol consumption in East Asians, but their associations with other cancers remain uncertain. ALDH2‐rs671 G>A and ADH1B‐rs1229984 G>A… read more here.
Keywords: cancer; aldh2 rs671; alcohol consumption;
Association between ALDH2 rs671 G>A polymorphism and gastric cancer susceptibility in Eastern Asia
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DOI: 10.18632/oncotarget.22060
Abstract: To date, the relationship between the aldehyde dehydrogenases-2 (ALDH2) rs671 G>A (Glu504Lys) polymorphism and gastric cancer (GC) risk has not been thoroughly elucidated. To derive a more precise estimation of the effect of the ALDH2… read more here.
Keywords: polymorphism; risk; rs671 polymorphism; aldh2 rs671 ... See more keywords
ALDH2 rs671 Polymorphism Likely a Risk Factor for Hemorrhagic Stroke: A Hospital-Based Study
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DOI: 10.2147/ijgm.s409183
Abstract: Background Hypertension is the main risk factor for hemorrhagic stroke. Aldehyde dehydrogenase 2 (ALDH2) may inhibit the occurrence of hypertension by anti-oxidative stress and vascular dilation. The purpose was to investigate the relationship of ALDH2… read more here.
Keywords: factor hemorrhagic; risk factor; aldh2 rs671; hemorrhagic stroke ... See more keywords
Aldehyde dehydrogenase 2 rs671G>A polymorphism and ischemic stroke risk in Chinese population: a meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s196175
Abstract: Introduction: Recently, molecular epidemiological studies have suggested that aldehyde dehydrogenase 2 (ALDH2) rs671 G>A polymorphism may be a risk factor for ischemic stroke (IS). However, the results reported have not been consistent. Methods: We conducted… read more here.
Keywords: meta analysis; aldh2 rs671; analysis; risk ... See more keywords
The Association between the ALDH2 rs671 Polymorphism and Athletic Performance in Japanese Power and Strength Athletes
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DOI: 10.3390/genes13101735
Abstract: The rs671 polymorphism is associated with the enzymatic activity of aldehyde dehydrogenase 2 (ALDH2), which is weakened by the A allele in East Asians. We recently reported the association of this polymorphism with the athletic… read more here.
Keywords: strength; polymorphism; strength athletes; power strength ... See more keywords