Articles with "aldh3a1" as a keyword



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Corneal haze phenotype in Aldh3a1-null mice: In vivo confocal microscopy and tissue imaging mass spectrometry.

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Published in 2017 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2016.12.017

Abstract: ALDH3A1 is a corneal crystallin that protects ocular tissues from ultraviolet radiation through catalytic and non-catalytic functions. In addition, ALDH3A1 plays a functional role in corneal epithelial homeostasis by simultaneously modulating proliferation and differentiation. We… read more here.

Keywords: phenotype; corneal; microscopy; corneal haze ... See more keywords
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Identification of a peptide ligand for human ALDH3A1 through peptide phage display: Prediction and characterization of protein interaction sites and inhibition of ALDH3A1 enzymatic activity

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Published in 2023 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2023.1161111

Abstract: Aldehyde dehydrogenase 3A1 (ALDH3A1) by oxidizing medium chain aldehydes to their corresponding carboxylic acids, is involved in the detoxification of toxic byproducts and is considered to play an important role in antioxidant cellular defense. ALDH3A1… read more here.

Keywords: peptide; activity; human aldh3a1; aldh3a1 ... See more keywords
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ALDH3A1 acts as a prognostic biomarker and inhibits the epithelial mesenchymal transition of oral squamous cell carcinoma through IL-6/STAT3 signaling pathway

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Published in 2020 at "Journal of Cancer"

DOI: 10.7150/jca.40171

Abstract: Objectives: Aldehyde dehydrogenase 3A1 (ALDH3A1) is a member of the ALDH superfamily and its relationship with oral squamous cell carcinoma (OSCC) still unknown. In our subject, we aimed to reveal the expression pattern and clinical… read more here.

Keywords: cell; oral squamous; squamous cell; expression ... See more keywords