Cu-Catalyzed Cyclization/Coupling of Alkenyl Aldimines with Arylzinc Reagents: Access to Indole-3-diarylmethanes.
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DOI: 10.1021/acs.orglett.2c02531
Abstract: We report a Cu(II)-catalyzed cyclization/coupling of alkenyl aldimines with arylzinc reagents to create indole-3-diarylmethane derivatives (Sapkota et al. ChemRxiv 2022, DOI: 10.26434/chemrxiv-2022-d6qn). The current reaction provides a unified modular route from readily available starting materials… read more here.
Keywords: catalyzed cyclization; aldimines arylzinc; cyclization coupling; alkenyl aldimines ... See more keywords