Dual effects of fructose on ChREBP and FoxO1/3α are responsible for AldoB up-regulation and vascular remodelling.
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DOI: 10.1042/cs20160251
Abstract: Increased production of methylglyoxal (MG) in vascular tissues is one of the causative factors for vascular remodelling in different subtypes of metabolic syndrome, including hypertension and insulin resistance. Fructose-induced up-regulation of aldolase B (AldoB) contributes… read more here.
Keywords: vascular remodelling; foxo1; aldob regulation; fructose induced ... See more keywords