Synthesis of Substrates for Aldolase-Catalysed Reactions: A Comparison of Methods for the Synthesis of Substituted Phenylacetaldehydes
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DOI: 10.1055/s-0036-1591963
Abstract: Methods for the synthesis of phenylacetaldehydes (oxidation, one-carbon chain extension) were compared by using the synthesis of 4-methoxyphenylacetaldehyde as a model example. Oxidations of 4-methoxyphenylethanol with activated DMSO (Swern oxidation) or manganese dioxide gave unsatisfactory… read more here.
Keywords: substrates aldolase; methods synthesis; substituted phenylacetaldehydes; aldolase catalysed ... See more keywords