Comparative Safety and Effectiveness of Aldosterone Antagonists Versus Beta-Blockers as Fourth Agents in Patients With Apparent Resistant Hypertension
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DOI: 10.1161/hypertensionaha.122.19280
Abstract: BACKGROUND: Limited evidence exists regarding long-term effectiveness and safety of aldosterone antagonists (AAs) versus beta blockers (BBs) as fourth-line antihypertensive agents in patients with resistant hypertension (RH). We evaluated the comparative effectiveness and safety of… read more here.
Keywords: safety; hypertension; versus beta; effectiveness ... See more keywords
The Mechanisms of Actions of Aldosterone and its Antagonists in Cardiovascular Disease.
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DOI: 10.2174/1381612825666190215100502
Abstract: BACKGROUND Aldosterone, through its actions on Mineralcorticosteroid Receptors (MR), controls fluid and electrolyte balance, but also exerts various direct deleterious actions on the vasculature. A number of aldosterone antagonists have been manufactured to reverse these… read more here.
Keywords: actions aldosterone; mechanisms actions; cardiovascular disease; mra ... See more keywords