Lipoprotein insulin resistance score and branched-chain amino acids increase after adrenalectomy for unilateral aldosterone-producing adenoma: a preliminary study
Sign Up to like & getrecommendations! Published in 2020 at "Endocrine"
DOI: 10.1007/s12020-020-02235-2
Abstract: Background and aims Primary aldosteronism (PA) due to unilateral aldosterone-producing adenoma (APA) is preferentially treated by unilateral adrenalectomy (ADX), but little is known about the changes in lipid and glucose metabolism that may occur after… read more here.
Keywords: amino acids; chain amino; producing adenoma; aldosterone producing ... See more keywords
Partial versus total adrenalectomy for the treatment of unilateral aldosterone-producing adenoma: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2021 at "Updates in Surgery"
DOI: 10.1007/s13304-021-01116-1
Abstract: Adrenalectomy is the first line of treatment in unilateral aldosterone-producing adenoma. Whether adrenalectomy should be performed using a cortex-sparing technique (partial adrenalectomy) or total adrenalectomy remains debatable. Therefore, this meta-analysis aims to evaluate the safety… read more here.
Keywords: adrenalectomy; producing adenoma; aldosterone producing; unilateral aldosterone ... See more keywords
Subtyping of primary aldosteronism with adrenal vein sampling: Hormone‐ and side‐specific effects of cosyntropin and metoclopramide
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DOI: 10.1016/j.surg.2017.09.032
Abstract: Background. Cosyntropin and metoclopramide can affect the subtyping of primary aldosteronism when used with adrenal vein sampling by exerting hormone‐ and side‐specific effects on cortisol and aldosterone secretion. We investigated how these stimuli affect the… read more here.
Keywords: index; adrenal vein; aldosterone; producing adenoma ... See more keywords
KCNJ5 mutation as a predictor for resolution of hypertension after surgical treatment of aldosterone-producing adenoma
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DOI: 10.1097/hjh.0000000000001578
Abstract: Objective: To investigate the effect of KCNJ5 mutations on the cure of hypertension in patients with aldosterone-producing adenoma (APA) after unilateral adrenalectomy. Methods: Our study included 142 patients with APA, who were detected with an… read more here.
Keywords: aldosterone producing; kcnj5 mutations; resolution hypertension; hypertension ... See more keywords
Identification of potential lncRNA‐miRNA‐mRNA regulatory network contributing to aldosterone‐producing adenoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17586
Abstract: Aldosterone‐producing adenoma (APA) is a common cause of secondary hypertension. This study aimed to explore the lncRNA‐miRNA‐mRNA competitive endogenous RNA (ceRNA) network to uncover molecular mechanism underlying APA. The mRNA and lncRNA expression data of… read more here.
Keywords: network; mirna mrna; aldosterone producing; lncrna mirna ... See more keywords
Aldosterone-producing adrenocortical carcinoma with myxoid differentiation in a cat.
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary clinical pathology"
DOI: 10.1111/vcp.12658
Abstract: A 10-year-old male neutered Persian cat was presented with an abdominal mass and history of weakness. Blood smear examination found marked elliptocytosis, and serum biochemical analysis revealed hypokalemia, hypochloremia, increased creatine kinase activity, and a… read more here.
Keywords: adrenocortical carcinoma; aldosterone; aldosterone producing; producing adrenocortical ... See more keywords
Aldosterone-Producing Adenomas: Genotypes and Phenotypes.
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DOI: 10.1161/hypertensionaha.117.09161
Abstract: See related article, pp 129–136 Primary aldosteronism (PA), which can be detected by aldosterone-to-renin ratio in its great majority, has come to be conceived as the most frequent form of secondary hypertension constituting ≈5% to… read more here.
Keywords: aldosterone producing; hypertension; adenomas genotypes; producing adenomas ... See more keywords
Tumor Cell Subtypes Based on the Intracellular Hormonal Activity in KCNJ5-Mutated Aldosterone-Producing Adenoma
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DOI: 10.1161/hypertensionaha.118.10907
Abstract: Aldosterone-producing adenomas (APAs) harbor marked intratumoral heterogeneity in terms of morphology, steroidogenesis, and genetics. However, an association of biological significance of morphologically identified tumor cell subtypes and genotypes is virtually unknown. KCNJ5 mutation is most… read more here.
Keywords: kcnj5; aldosterone producing; mutated apas; kcnj5 mutated ... See more keywords
Cellular and Genetic Causes of Idiopathic Hyperaldosteronism
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DOI: 10.1161/hypertensionaha.118.11086
Abstract: Primary aldosteronism affects ≈5% to 10% of hypertensive patients and has unilateral and bilateral forms. Most unilateral primary aldosteronism is caused by computed tomography-detectable aldosterone-producing adenomas, which express CYP11B2 (aldosterone synthase) and frequently harbor somatic… read more here.
Keywords: aldosterone; iha; aldosterone producing; iha adrenals ... See more keywords
Aldosterone and 18-Oxocortisol Coaccumulation in Aldosterone-Producing Lesions
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DOI: 10.1161/hypertensionaha.118.11243
Abstract: Primary aldosteronism is a secondary hypertensive disease caused by autonomous aldosterone production that often caused by an aldosterone-producing adenoma (APA). Immunohistochemistry of aldosterone synthase (CYP11B2) shows the presence of aldosterone-producing cell clusters (APCCs) even in… read more here.
Keywords: aldosterone; primary aldosteronism; aldosterone oxocortisol; aldosterone producing ... See more keywords
Changes of the CYP11B2 Expressing Zona Glomerulosa in Human Adrenals From Birth to 40 Years of Age
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DOI: 10.1161/hypertensionaha.122.19052
Abstract: Background: Aldosterone synthase (CYP11B2) antibodies for immunohistochemistry, enables to visualize aldosterone-producing zona glomerulosa (ZG), aldosterone-producing micronodules, and aldosterone-producing adenomas. The architecture of the ZG differs in old versus young age but the evolution of the… read more here.
Keywords: aldosterone producing; area; zona glomerulosa; age ... See more keywords