The neuropeptide substance P regulates aldosterone secretion in human adrenals
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DOI: 10.1038/s41467-020-16470-8
Abstract: Aldosterone, produced by the adrenals and under the control of plasma angiotensin and potassium levels, regulates hydromineral homeostasis and blood pressure. Here we report that the neuropeptide substance P (SP) released by intraadrenal nerve fibres, stimulates aldosterone… read more here.
Keywords: aldosterone production; aldosterone secretion; neuropeptide substance; aldosterone ... See more keywords
Calneuron 1 Increased Ca2+ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma
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DOI: 10.1161/hypertensionaha.117.10205
Abstract: Aldosterone production is initiated by angiotensin II stimulation and activation of intracellular Ca2+ signaling. In aldosterone-producing adenoma (APA) cells, the activation of intracellular Ca2+ signaling is independent of the renin–angiotensin–aldosterone systems. The purpose of our… read more here.
Keywords: aldosterone production; caln1 expression; hac15 cells; aldosterone ... See more keywords