The neuropeptide substance P regulates aldosterone secretion in human adrenals
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DOI: 10.1038/s41467-020-16470-8
Abstract: Aldosterone, produced by the adrenals and under the control of plasma angiotensin and potassium levels, regulates hydromineral homeostasis and blood pressure. Here we report that the neuropeptide substance P (SP) released by intraadrenal nerve fibres, stimulates aldosterone… read more here.
Keywords: aldosterone production; aldosterone secretion; neuropeptide substance; aldosterone ... See more keywords
078 Chronic sleep and circadian disruption differentially affects blood pressure, renal sodium retention, and aldosterone secretion
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DOI: 10.1093/sleep/zsab072.077
Abstract: Chronic sleep restriction (CSR) and recurrent circadian disruption (RCD; e.g., rotating shiftwork) can increase an individual’s risk of cardiovascular and kidney disease. However, no study has assessed whether CSR and RCD together increase blood pressure… read more here.
Keywords: blood pressure; sodium; aldosterone secretion; secretion ... See more keywords
Autonomous Aldosterone Secretion in Patients with Adrenal Incidentaloma
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DOI: 10.3390/biomedicines10123075
Abstract: In recent years, research has emphasized the significance of mild clinical and biochemical presentations of primary aldosteronism (PA) that do not meet current diagnostic criteria of the syndrome. In this study, we assessed the prevalence… read more here.
Keywords: aldosterone secretion; autonomous aldosterone; aldosterone; patients adrenal ... See more keywords
YM750, an ACAT Inhibitor, Acts on Adrenocortical Cells to Inhibit Aldosterone Secretion Due to Depolarization
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DOI: 10.3390/ijms232112803
Abstract: Primary aldosteronism (PA) is considered the most common form of secondary hypertension, which is associated with excessive aldosterone secretion in the adrenal cortex. The cause of excessive aldosterone secretion is the induction of aldosterone synthase… read more here.
Keywords: aldosterone secretion; expression; secretion; adrenocortical cells ... See more keywords