The Interplay between the Immune System, the Renin Angiotensin Aldosterone System (RAAS) and RAAS Inhibitors May Modulate the Outcome of COVID‐19: A Systematic Review
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DOI: 10.1002/jcph.1852
Abstract: Since the discovery of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), numerous research has been undertaken to delineate the various effects of the virus which manifests in many ways all over the body. The association… read more here.
Keywords: system; angiotensin aldosterone; covid; renin angiotensin ... See more keywords
Anthracycline-induced cardiotoxicity and renin-angiotensin-aldosterone system—from molecular mechanisms to therapeutic applications
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DOI: 10.1007/s10741-020-09977-1
Abstract: Few millions of new cancer cases are diagnosed worldwide every year. Due to significant progress in understanding cancer biology and developing new therapies, the mortality rates are decreasing with many of patients that can be… read more here.
Keywords: system; angiotensin aldosterone; anthracycline induced; renin angiotensin ... See more keywords
Renin Angiotensin Aldosterone System Inhibitors in Chronic Kidney Disease: A Difficult Equation
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DOI: 10.1007/s40256-021-00467-9
Abstract: Chronic kidney disease (CKD) is a global health problem and is strongly associated with hypertension (HTN) and impaired quality of life. Managing HTN with agents that block the renin angiotensin aldosterone system (RAAS) remains the… read more here.
Keywords: difficult equation; angiotensin aldosterone; chronic kidney; renin angiotensin ... See more keywords
"Permissive AKI" with treatment of heart failure.
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DOI: 10.1016/j.kint.2019.07.003
Abstract: Renin-angiotensin-aldosterone system inhibitors have proven clinical benefit in management of patients with heart failure with reduced ejection fraction. However, there are no guidelines to manage decline in kidney function that occurs with initiation and titration… read more here.
Keywords: heart; angiotensin aldosterone; heart failure; renin angiotensin ... See more keywords
Use of renin-angiotensin-aldosterone system blockade in controversial chronic kidney disease populations.
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DOI: 10.1016/j.medcli.2020.12.025
Abstract: Renin-angiotensin-aldosterone system blockers have shown to be effective in controlling blood pressure and proteinuria, slowing the progression to end stage renal disease and reducing cardiovascular risk, so they are the mainstream treatment of hypertension in… read more here.
Keywords: angiotensin aldosterone; chronic kidney; disease; renin angiotensin ... See more keywords
THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PREGNANT RAT
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DOI: 10.1097/01.hjh.0000838428.32272.52
Abstract: Objective: Preeclampsia is the leading cause of maternal and fetal morbidity and mortality in the United States, affecting ~2–5% of all pregnancies. Women with a history of preeclampsia have a 4-fold increased risk for developing… read more here.
Keywords: aldosterone; angiotensin aldosterone; aldosterone system; angii ... See more keywords
DEVELOPMENT OF A TARGETED PROTEOMICS ASSAY FOR QUANTIFICATION OF ANGIOTENSIN PEPTIDES IN THE RENIN ANGIOTENSIN ALDOSTERONE SYSTEM
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DOI: 10.1097/01.hjh.0000838464.48656.e7
Abstract: Objective: The canonical renin–angiotensin aldosterone system (RAAS) has been extensively studied and methods are available for use clinically to assess hypertension. The non-canonical axis of the RAAS (consists of angiotensin 1–7, angiotensin 1–9, angiotensin-converting enzyme… read more here.
Keywords: angiotensin; angiotensin aldosterone; aldosterone system; ang ... See more keywords
Association of Renin Angiotensin Aldosterone System Inhibitors and Outcomes of Hospitalized Patients With COVID-19
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DOI: 10.1097/ccm.0000000000005627
Abstract: OBJECTIVES: To determine the association of prior use of renin-angiotensin-aldosterone system inhibitors (RAASIs) with mortality and outcomes in hospitalized patients with COVID-19. DESIGN: Retrospective observational study. SETTING: Multicenter, international COVID-19 registry. Subjects: Adult hospitalized COVID-19… read more here.
Keywords: angiotensin aldosterone; aldosterone system; system inhibitors; mortality ... See more keywords
Coronavirus disease 2019, hypertension, and renin–angiotensin–aldosterone system inhibitors
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DOI: 10.1097/hco.0000000000000982
Abstract: Purpose of review The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mostly uses the angiotensin-converting enzyme 2 (ACE-2) as cellular receptor for entering the host cells. Some, but not all, animal studies have shown that… read more here.
Keywords: angiotensin aldosterone; coronavirus disease; aldosterone system; raas inhibitors ... See more keywords
Adverse effects during treatment with renin-angiotensin-aldosterone system inhibitors; should we stay or should we stop?
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DOI: 10.1097/mnh.0000000000000878
Abstract: PURPOSE OF REVIEW To discuss recent evidence on the benefits and harms of stopping therapy with renin-angiotensin-aldosterone system inhibitors (RAASi) after the occurrence of adverse events or in patients with advanced chronic kidney disease (CKD).… read more here.
Keywords: system inhibitors; aldosterone system; angiotensin aldosterone; renin angiotensin ... See more keywords
Comparison of infection risks and clinical outcomes in patients with and without SARS‐CoV‐2 lung infection under renin–angiotensin–aldosterone system blockade: Systematic review and meta‐analysis
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DOI: 10.1111/bcp.14660
Abstract: Angiotensin‐converting enzyme‐2 (ACE2) is the receptor for SARS‐CoV‐2. Animal studies suggest that renin–angiotensin–aldosterone system (RAAS) blockers might increase the expression of ACE2 and potentially increase the risk of SARS‐CoV‐2 infection. read more here.
Keywords: angiotensin aldosterone; infection; renin angiotensin; sars cov ... See more keywords