Defined Alginate Hydrogels Support Spinal Cord Organoid Derivation, Maturation, and Modeling of Spinal Cord Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202342
Abstract: In the process of generating organoids, basement membrane extracts or Matrigel are often used to encapsulate cells but they are poorly defined and contribute to reproducibility issues. While defined hydrogels are increasingly used for organoid… read more here.
Keywords: cord; cord organoid; alginate hydrogels; organoid derivation ... See more keywords
Development of Gelatin-Alginate Hydrogels for Burn Wound Treatment.
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201900123
Abstract: Hydrogels are interesting as wound dressing for burn wounds to maintain a moist environment. Especially gelatin and alginate based wound dressings show strong potential. Both polymers are modified by introducing photocrosslinkable functionalities and combined to… read more here.
Keywords: alginate; hydrogels burn; alginate hydrogels; development gelatin ... See more keywords
A comparative study of mesenchymal stems cells cultured as cell-only aggregates and in encapsulated hydrogels.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of tissue engineering and regenerative medicine"
DOI: 10.1002/term.3257
Abstract: There is increasing evidence that cells cultured in three-dimensional (3D) settings have superior performance compared to their traditional counterparts in monolayers. This has been attributed to cell-cell and cell-ECM interactions that more closely resemble the… read more here.
Keywords: cells cultured; alginate hydrogels; comparative study; cell aggregates ... See more keywords
Alginate Hydrogels with Tuneable Properties.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in biochemical engineering/biotechnology"
DOI: 10.1007/10_2020_161
Abstract: Alginate is a material that has many biomedical applications due to its low toxicity and a variety of favourable physical properties. In particular, the ease in which hydrogels are formed from alginate and the variety… read more here.
Keywords: alginate hydrogels; hydrogels tuneable; chemistry; properties alginate ... See more keywords
Alginate hydrogels for bone tissue engineering, from injectables to bioprinting: A review.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.115514
Abstract: This review focuses on recently developed alginate injectable hydrogels and alginate composites for applications in bone tissue regeneration, and it evaluates the alternatives to overcome the problems that avoid their utilization in the field. Section… read more here.
Keywords: bone tissue; alginate hydrogels; tissue; review ... See more keywords
Biocompatible and self-recoverable succinoglycan dialdehyde-crosslinked alginate hydrogels for pH-controlled drug delivery.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.116934
Abstract: We fabricated polysaccharide-based hydrogels, which are biocompatible, self-recoverable and pH-sensitive. Succinoglycan dialdehyde (SGDA) was first synthesized from bacterial succinoglycan directly isolated from Sinorhizobium meliloti and then hydrazine-functionalized alginate (HZ-Alg) was prepared to form SGDA-crosslinked alginate… read more here.
Keywords: self recoverable; alginate hydrogels; biocompatible self; crosslinked alginate ... See more keywords
Dual crosslinked alginate hydrogels by riboflavin as photoinitiator.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.03.134
Abstract: Photodegradation behavior of riboflavin (RF) as photoinitiator and photosensitizer was investigated. When the visible light was irradiated to RF, the radical activation and decomposition of RF was induced by reactive oxygen species (ROS) that has… read more here.
Keywords: hydrogels riboflavin; alginate hydrogels; crosslinked alginate; dual crosslinked ... See more keywords
Enzymes Encapsulated within Alginate Hydrogels: Bioelectrocatalysis and Electrochemiluminescence Applications
Sign Up to like & getrecommendations! Published in 2022 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.2c03389
Abstract: A simple procedure to incorporate enzymes (horseradish peroxidase, HRP, and lactate oxidase, LOx) within alginate hydrogels is reported with electrochemiluminescence (ECL) used to detect the enzymatic reactions with the corresponding substrates. First, HRP and LOx… read more here.
Keywords: hydrogen peroxide; encapsulated within; alginate hydrogels; within alginate ... See more keywords
Cell-Instructive Alginate Hydrogels Targeting RhoA.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.8b00436
Abstract: Cellular processes involve dynamic rearrangement of the cytoskeleton. The GTPase RhoA plays a fundamental role in controlling cytoskeletal architecture. The phenotypic stability of chondrocytes is enhanced through inhibition of RhoA, whereas RhoA activation leads to… read more here.
Keywords: alginate; rhoa; alginate hydrogels; hydrogels targeting ... See more keywords
3D-Printable Bioactivated Nanocellulose-Alginate Hydrogels.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b02756
Abstract: We describe herein a nanocellulose-alginate hydrogel suitable for 3D printing. The composition of the hydrogel was optimized based on material characterization methods and 3D printing experiments, and its behavior during the printing process was studied… read more here.
Keywords: alginate; nanocellulose alginate; hydrogel; alginate hydrogels ... See more keywords
Production of reactive species in alginate hydrogels for cold atmospheric plasma-based therapies
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52673-w
Abstract: In the last years, great advances have been made in therapies based in cold atmospheric plasmas (CAP). CAP generate reactive oxygen and nitrogen species (RONS) which can be transferred to liquids. These CAP activated liquids… read more here.
Keywords: reactive species; plasma; production reactive; cold atmospheric ... See more keywords