Chitosan alginate nanoparticles as a platform for the treatment of diabetic and non-diabetic pressure ulcers: formulation and in vitro/in vivo evaluation.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120963
Abstract: Chitosan and alginate are natural bioactive polymers with wound healing properties, in addition to chitosan's anti-bacterial properties. In this study, these two polymers were combined in a drug-free nanosystem with positive or negative surface charges,… read more here.
Keywords: diabetic pressure; pressure ulcers; chitosan alginate; non diabetic ... See more keywords
Smart nanocomposites of chitosan/alginate nanoparticles loaded with copper oxide as alternative nanofertilizers
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Science: Nano"
DOI: 10.1039/d0en00797h
Abstract: A chitosan and sodium alginate complex acts as a biodegradable shell to release nanoscaled nutrients, CuO nanoparticles, as an alternative smart delivery nanofertilizer. read more here.
Keywords: alginate nanoparticles; loaded copper; nanocomposites chitosan; nanoparticles loaded ... See more keywords
Investigating preparation and characterisation of diphtheria toxoid‐loaded on sodium alginate nanoparticles
Sign Up to like & getrecommendations! Published in 2022 at "IET Nanobiotechnology"
DOI: 10.1049/nbt2.12088
Abstract: Abstract This paper aims to investigate the preparation and characterisation of the alginate nanoparticles (NPs) as antigen delivery system loaded by diphtheria toxoid (DT). For this purpose, both the loading capacity (LC) and Loading efficiency… read more here.
Keywords: alginate nanoparticles; sodium alginate; diphtheria toxoid; alginate ... See more keywords
Pickering emulsions stabilized by hydrophobically modified alginate nanoparticles: Preparation and pH-responsive performance in vitro
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Dispersion Science and Technology"
DOI: 10.1080/01932691.2017.1320223
Abstract: ABSTRACT pH-responsive Pickering emulsions were prepared, taking the hydrophobic modified calcium alginate nanoparticles (MCA) of pH sensitivity as emulsifiers. The MCAs were obtained via gelation between Ca2+ in emulsion and alginate sodium that reacted with… read more here.
Keywords: alginate; hydrophobically modified; pickering emulsions; emulsions stabilized ... See more keywords
Metformin‐loaded alginate nanoparticles as an effective antidiabetic agent for controlled drug release
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.12672
Abstract: Present modalities for the diagnosis and treatment of diabetes still suffer from certain limitations such as erratic absorption, need of high dose, poor sensitivity or specificity, resistance, substantial morbidity and mortality, long‐term complications, and patient‐to‐patient… read more here.
Keywords: loaded alginate; metformin loaded; effective antidiabetic; antidiabetic agent ... See more keywords
Synthesis and Characterization of Magnetite-Alginate Nanoparticles for Enhancement of Nickel and Cobalt Ion Adsorption from Wastewater
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Nanomaterials"
DOI: 10.1155/2019/6326012
Abstract: Superparamagnetic magnetite-alginate nanoparticles (M-AlgNPs) were synthesized utilizing a coprecipitation method. Then, the prepared M-AlgNPs were characterized via Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction spectroscopy (XRD) to affirm the formation and the crystallinity of… read more here.
Keywords: adsorption; alginate nanoparticles; spectroscopy; magnetite alginate ... See more keywords
Electrosprayed Alginate Nanoparticles as CRISPR Plasmid DNA Delivery Carrier: Preparation, Optimization, and Characterization
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceuticals"
DOI: 10.3390/ph13080158
Abstract: Therapeutic gene editing is becoming more feasible with the emergence of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein (Cas) system. However, the successful implementation of CRISPR/Cas9-based therapeutics requires a safe and efficient in… read more here.
Keywords: preparation optimization; crispr; delivery; optimization characterization ... See more keywords
Enhancing Colistin Activity against Colistin-Resistant Escherichia coli through Combination with Alginate Nanoparticles and Small Molecules
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15060682
Abstract: Bacterial resistance to antibiotics has become a major public health problem worldwide, with the yearly number of deaths exceeding 700,000. To face this well-acknowledged threat, new molecules and therapeutic methods are considered. In this context,… read more here.
Keywords: alginate nanoparticles; alg nps; escherichia coli; colistin ... See more keywords
Enhanced Nasal Deposition and Anti-Coronavirus Effect of Favipiravir-Loaded Mucoadhesive Chitosan–Alginate Nanoparticles
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122680
Abstract: Favipiravir (FVR) is a repurposed antiviral drug for treating mild to moderate cases of the novel coronavirus disease 2019 (COVID-19). However, its poor solubility and permeability limit its clinical efficacy. To overcome its physicochemical and… read more here.
Keywords: alginate nanoparticles; coronavirus; chitosan alginate; favipiravir ... See more keywords