Crystalline Antibody-Laden Alginate Particles: A Platform for Enabling High Concentration Subcutaneous Delivery of Antibodies.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202202370
Abstract: Subcutaneous administration is a desired route for monoclonal antibodies (mAbs). However, formulating mAbs for small injection volumes at high concentrations with suitable stability and injectability is a significant challenge. Here we present a platform technology… read more here.
Keywords: alginate particles; crystalline antibody; antibody laden; high concentration ... See more keywords
Producing shape-engineered alginate particles using viscoplastic fluids.
Sign Up to like & getrecommendations! Published in 2022 at "Soft matter"
DOI: 10.1039/d2sm00621a
Abstract: Non-spherical hydrogel particles are of fundamental interest and can find use in a variety of applications ranging from pharmaceuticals to biomedical to food. Here, we report a new method that leverages the yield stress property… read more here.
Keywords: shape engineered; yield stress; viscoplastic fluids; alginate particles ... See more keywords