Alignment of single-cell trajectories to compare cellular expression dynamics
Sign Up to like & getrecommendations! Published in 2018 at "Nature Methods"
DOI: 10.1038/nmeth.4628
Abstract: Single-cell RNA sequencing and high-dimensional cytometry can be used to generate detailed trajectories of dynamic biological processes such as differentiation or development. Here we present cellAlign, a quantitative framework for comparing expression dynamics within and… read more here.
Keywords: single cell; alignment single; expression dynamics; cell trajectories ... See more keywords
BBKNN: fast batch alignment of single cell transcriptomes
Sign Up to like & getrecommendations! Published in 2020 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz625
Abstract: MOTIVATION Increasing numbers of large scale single cell RNA-Seq projects are leading to a data explosion, which can only be fully exploited through data integration. A number of methods have been developed to combine diverse… read more here.
Keywords: single cell; alignment single; bbknn fast; batch alignment ... See more keywords