Ni-Catalyzed Suzuki-Miyaura Cross-Coupling of Aliphatic Amides on the Benchtop.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b03434
Abstract: Suzuki-Miyaura cross-couplings of amides offer an approach to the synthesis of ketones that avoids the use of basic or pyrophoric nucleophiles. However, these reactions require glovebox manipulations, thus limiting their practicality. We report a benchtop… read more here.
Keywords: suzuki miyaura; aliphatic amides; miyaura cross;
Nickel-Catalyzed Annulation of Aliphatic Amides with AlkynylÂsilanes: An Expeditious Approach to Five-Membered Lactams
Sign Up to like & getrecommendations! Published in 2020 at "Synlett"
DOI: 10.1055/s-0037-1610756
Abstract: An expeditious approach for the synthesis of diverse five-membered lactams through nickel-catalyzed annulation of the C(sp3)–H bonds of aliphatic amides with alkynylsilanes assisted by an 8-aminoquinolinyl directing group is reported, delivering the corresponding lactam derivatives… read more here.
Keywords: five membered; expeditious approach; aliphatic amides; membered lactams ... See more keywords