New protocol of copper-catalyzed oxidative C(CO)C bond cleavage of aryl and aliphatic ketones to organic acids using O2 as the terminal oxidant
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Catalysis"
DOI: 10.1016/j.jcat.2016.12.016
Abstract: Catalytic oxidation of CC bond is a key technology to transform petroleum-based as well as sustainable biomass feedstock into more valuable oxygenates. We herein describe a convenient and useful oxidation strategy of converting ketones into… read more here.
Keywords: bond; aliphatic ketones; copper; terminal oxidant ... See more keywords
Reductive coupling of phthalic anhydrides with aliphatic ketones by low-valent titanium: Unusual two-to-one coupling for preparation of 3,3-disubstituted phthalides
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.130820
Abstract: Abstract The reductive coupling of phthalic anhydrides with acetone by Zn-TiCl4 in THF gave two-to-one and one-to-one coupled products. The coupled products were transformed to 3,3-diisopropyl-, 3-isopropylidene-, and 3-isopropylphthalides. In addition, the reductive coupling of… read more here.
Keywords: coupling phthalic; two one; aliphatic ketones; phthalic anhydrides ... See more keywords
Electrochemical synthesis of 2-alkyl-4-phenylalkan-2-ols via cathodic reductive coupling of alkynes with unactivated aliphatic ketones.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc06819b
Abstract: Herein, we present an efficient electrochemical method for synthesizing 2-alkyl-4-phenylalkan-2-ols through an electrochemically driven cathodic reductive coupling of the terminal and internal acetylenes with unactivated aliphatic ketones under mild conditions. The process proceeds through a… read more here.
Keywords: aliphatic ketones; reductive coupling; cathodic reductive; unactivated aliphatic ... See more keywords
Multiple remote C(sp3)–H functionalizations of aliphatic ketones via bimetallic Cu–Pd catalyzed successive dehydrogenation
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc05370e
Abstract: The dehydrogenation-triggered multiple C(sp3)–H functionalizations at remote positions γ, δ or ε, ζ to carbonyl groups of aliphatic ketones with aryl/alkenyl carboxylic acids as coupling partners have been achieved using a bimetallic Cu–Pd catalyst system.… read more here.
Keywords: multiple remote; successive dehydrogenation; sp3 functionalizations; bimetallic catalyzed ... See more keywords