Alisporivir rescues defective mitochondrial respiration in Duchenne muscular dystrophy
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DOI: 10.1016/j.phrs.2017.09.001
Abstract: &NA; Duchenne muscular dystrophy (DMD) is a severe muscle disease of known etiology without effective, or generally applicable therapy. Mitochondria are affected by the disease in animal models but whether mitochondrial dysfunction is part of… read more here.
Keywords: muscle; alisporivir; duchenne muscular; muscular dystrophy ... See more keywords
Targeting Artemisinin-Resistant Malaria by Repurposing the Anti-Hepatitis C Virus Drug Alisporivir
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DOI: 10.1128/aac.00392-22
Abstract: The emergence of Plasmodium falciparum resistance raises an urgent need to find new antimalarial drugs. Here, we report the rational repurposing of the anti-hepatitis C virus drug, alisporivir, a nonimmunosuppressive analog of cyclosporin A, against… read more here.
Keywords: alisporivir; anti hepatitis; artemisinin resistant; repurposing anti ... See more keywords