Biochemical and Imaging Analysis of ALIX Function in Endosomal Trafficking of Arabidopsis Protein Cargoes.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0767-1_5
Abstract: ALIX/Bro1 proteins are conserved in eukaryotes where they enable targeted trafficking of membrane-associated proteins through the late endosome route to the vacuole. For this, ALIX/Bro1 proteins associate with the endosomal sorting complex required for transport… read more here.
Keywords: alix function; function endosomal; alix; protein cargoes ... See more keywords
The Flemmingsome reveals an ESCRT-to-membrane coupling via ALIX/syntenin/syndecan-4 required for completion of cytokinesis
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15205-z
Abstract: Cytokinesis requires the constriction of ESCRT-III filaments on the side of the midbody, where abscission occurs. After ESCRT recruitment at the midbody, it is not known how the ESCRT-III machinery localizes to the abscission site.… read more here.
Keywords: escrt iii; abscission site; alix; abscission ... See more keywords
PYRE insertion within HIV-1 subtype C p6-Gag functions as an ALIX-dependent late domain
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-27162-1
Abstract: ALG-2 interacting protein X (ALIX) links HIV-1 Gag to the components of ESCRT-III. HIV-1 engages the ALIX via its nucleocapsid and LYPXnL motif in p6. Overexpression of ALIX corrects the release defect of PTAP deleted… read more here.
Keywords: pyre insertion; ptap; pyre; alix ... See more keywords
Arabidopsis ALIX Regulates Stomatal Aperture and Turnover of Abscisic Acid Receptors
Sign Up to like & getrecommendations! Published in 2019 at "Plant Cell"
DOI: 10.1105/tpc.19.00399
Abstract: ALIX mediates endosomal trafficking and turnover of abscisic acid receptors through the ESCRT/MVB pathway, modulating abscisic acid–mediated inhibition of plant growth and stomatal aperture. The plant endosomal trafficking pathway controls the abundance of membrane-associated soluble… read more here.
Keywords: abscisic acid; turnover abscisic; stomatal aperture; alix ... See more keywords
LncRNA446 Regulates Tight Junctions by Inhibiting the Ubiquitinated Degradation of Alix after Porcine Epidemic Diarrhea Virus Infection
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.01884-22
Abstract: Porcine epidemic diarrhea is an acute, highly contagious enteric viral disease severely affecting the pig industry, for which current vaccines are inefficient due to the high variability of PEDV. Because PEDV infection can lead to… read more here.
Keywords: infection; pedv infection; porcine epidemic; epidemic diarrhea ... See more keywords
Influence of CCL2-mediated modulation of ALIX in the budding and replication of viruses from multiple families
Sign Up to like & getrecommendations! Published in 2025 at "mBio"
DOI: 10.1128/mbio.02241-25
Abstract: ABSTRACT Signaling by C-C motif ligand 2 (CCL2), a β-chemokine, modulates HIV-1 budding and release by mobilizing ALG-2-interacting protein X (ALIX) from the F-actin cytoskeleton to the cytosol. Immunodepleting CCL2 in the medium sequesters ALIX… read more here.
Keywords: replication; ccl2 signaling; release; ccl2 ... See more keywords