Asymmetric Organocatalysis in the Remote (3 + 2)-Cycloaddition to 4-(Alk-1-en-1-yl)-3-cyanocoumarins
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DOI: 10.1021/acs.orglett.3c01189
Abstract: The application of organocatalytic bifunctional activation in the remote (3 + 2)-cycloaddition between 4-(alk-1-en-1-yl)-3-cyanocoumarins and imines derived from salicylaldehyde is demonstrated. Products, bearing two biologically relevant units, have been obtained with good chemical and stereochemical… read more here.
Keywords: remote cycloaddition; alk cyanocoumarins; cycloaddition alk; asymmetric organocatalysis ... See more keywords