Identification of novel ALK2 inhibitors and their effect on cancer cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.08.016
Abstract: Bone morphogenetic protein 9 (BMP9), a member of the TGF-β superfamily, is considered a regulator of glucose homeostasis as well as a neuronal differentiation factor. BMP9 induces phosphorylation of Smad1/5 through activin receptor-like kinase 1… read more here.
Keywords: alk2 inhibitors; novel alk2; identification novel; cancer cells ... See more keywords
Recent Advances in ALK2 Inhibitors
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c02983
Abstract: Activin receptor-like kinase-2 (ALK2) is a type I bone morphogenetic protein (BMP) receptor which has a role in biological processes that control the development of bone, heart, brain, and other tissue. Gain of function mutations… read more here.
Keywords: advances alk2; alk2 inhibitors; recent advances;