Vaccination with an alkaline extract of Histoplasma capsulatum packaged in glucan particles confers protective immunity in mice.
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DOI: 10.1016/j.vaccine.2018.04.047
Abstract: Infection with the dimorphic fungus, Histoplasma capsulatum, occurs world-wide, but North and South America are regions of high endemicity. Interventions to mitigate exposure and consequent disease are limited to remediating a habitat harboring the fungus.… read more here.
Keywords: alkaline extract; glucan particles; histoplasma capsulatum;