Structural insight into a novel indole prenyltransferase in hapalindole-type alkaloid biosynthesis.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.12.039
Abstract: FamD1 is a novel CloQ/NphB-family indole prenyltransferase which involves in hapalindole-type alkaloid biosynthesis. Here the native FamD1 structure and three protein-ligand complexes are analyzed to investigate the molecular basis of substrate binding and catalysis. FamD1… read more here.
Keywords: hapalindole type; indole prenyltransferase; type alkaloid; alkaloid biosynthesis ... See more keywords
Exploration of the Mechanisms of Differential Indole Alkaloid Biosynthesis in Dedifferentiated and Cambial Meristematic Cells of Catharanthus roseus Using Transcriptome Sequencing
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DOI: 10.3389/fgene.2022.867064
Abstract: Catharanthus roseus produces terpenoid indole alkaloids (TIAs) of high medicinal importance. The current research focuses on finding an efficient production system such as cell suspension cultures for high TIA concentrations. Catharanthus roseus cambial meristematic cells… read more here.
Keywords: meristematic cells; alkaloid biosynthesis; biosynthesis; catharanthus roseus ... See more keywords
Transcriptome and metabolome profiling of the medicinal plant Veratrum mengtzeanum reveal key components of the alkaloid biosynthesis
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DOI: 10.3389/fgene.2023.1023433
Abstract: Veratrum mengtzeanum is the main ingredient for Chinese folk medicine known as “Pimacao” due to its unique alkaloids. A diverse class of plant-specific metabolites having key pharmacological activities. There are limited studies on alkaloid synthesis… read more here.
Keywords: leaves roots; alkaloid biosynthesis; biosynthesis; veratrum mengtzeanum ... See more keywords
Quinolizidine Alkaloid Biosynthesis in Lupins and Prospects for Grain Quality Improvement
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DOI: 10.3389/fpls.2017.00087
Abstract: Quinolizidine alkaloids (QAs) are toxic secondary metabolites found within the genus Lupinus, some species of which are commercially important grain legume crops including Lupinus angustifolius (narrow-leafed lupin, NLL), L. luteus (yellow lupin), L. albus (white… read more here.
Keywords: biosynthesis lupins; lupin; quinolizidine alkaloid; alkaloid biosynthesis ... See more keywords
Involvement of PtPHR1 in phosphates starvation-induced alkaloid biosynthesis in Pinellia ternata (Thunb.) Breit
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DOI: 10.3389/fpls.2022.914648
Abstract: Nowadays, because of the great benefit to human health, more and more efforts have been made to increase the production of alkaloids in Pinellia ternata (Thunb.) Breit. Phosphate (Pi) plays a critical role in plant… read more here.
Keywords: alkaloid biosynthesis; starvation; ptphr1; phr1 ... See more keywords
Transcriptomic analysis of genes related to alkaloid biosynthesis and the regulation mechanism under precursor and methyl jasmonate treatment in Dendrobium officinale
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.941231
Abstract: Dendrobium officinale is both a traditional herbal medicine and a plant of high ornamental and medicinal value. Alkaloids, especially terpenoid indole alkaloids (TIAs), with pharmacological activities are present in the tissues of D. officinale. A… read more here.
Keywords: alkaloid biosynthesis; related alkaloid; analysis; precursor ... See more keywords