New phthalideisoquinoline hemiacetal alkaloid derivatives from Corydalis decumbens.
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DOI: 10.1016/j.fitote.2020.104494
Abstract: Two new phthalideisoquinoline hemiacetal alkaloid derivatives, named corybensines A and B (1 and 2), and four known alkaloids (3-6) were isolated from the bulbs of Corydalis decumbens. Their structures were characterized by analysis of 1D/2D… read more here.
Keywords: new phthalideisoquinoline; alkaloid derivatives; derivatives corydalis; corydalis decumbens ... See more keywords
New Structural Modifications of Cotarnine Alkaloid Derivatives: Cotarnone and Dihydrocotarnine
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DOI: 10.1134/s1070363220020127
Abstract: Abstract Simplest derivatives of the cotarnine alkaloid, like cotarnone and 1,2-dihydrocotarnine, undergo electrophilic Einhorn acylamidomethylation (with 60–95% yield) and sulfochlorination with chlorosulfonic acid at position 5. At the same time cotarnone and its derivatives undergo… read more here.
Keywords: cotarnone dihydrocotarnine; modifications cotarnine; structural modifications; alkaloid derivatives ... See more keywords
Synthesis and Antileukemia Activity Evaluation of Benzophenanthridine Alkaloid Derivatives
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DOI: 10.3390/molecules27123934
Abstract: Thirty-three benzophenanthridine alkaloid derivatives (1a–1u and 2a–2l) were synthesized, and their cytotoxic activities against two leukemia cell lines (Jurkat Clone E6-1 and THP-1) were evaluated in vitro using a Cell Counting Kit-8 (CCK-8) assay. Nine… read more here.
Keywords: benzophenanthridine alkaloid; activity; antileukemia activity; alkaloid derivatives ... See more keywords
Synthesis and Structure–Activity Analysis of Novel Potential Antifungal Cyclotryptamine Alkaloid Derivatives
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DOI: 10.3390/molecules28062617
Abstract: A total of 39 novel cyclotryptamine alkaloid derivatives were prepared from 2-(1H-indol-3-yl) acetonitrile. The prepared compounds were evaluated against six plant pathogen fungi. Bioassay results revealed that most of the compounds displayed higher in vitro… read more here.
Keywords: novel potential; activity; cyclotryptamine alkaloid; alkaloid derivatives ... See more keywords