Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of Ketones.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04101
Abstract: Most ligands applied for asymmetric hydrogenation are synthesized via multistep reactions with expensive chemical reagents. Herein, a series of novel and easily accessed cinchona-alkaloid-based NNP ligands have been developed in two steps. By combining [Ir(COD)Cl]2,… read more here.
Keywords: cinchona alkaloid; derived nnp; alkaloid derived; nnp ligand ... See more keywords
Cinchona Alkaloid Derived Iodide Catalyzed Enantioselective Oxidative α-Amination of Carbonyl Compounds toward the Construction of Spiroindolyloxindole.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04118
Abstract: Novel cinchona alkaloid derived iodide catalysts were developed for the enantioselective oxidative α-amination of 2-oxindoles, providing various functionalized spiropyrrolidine oxindoles in high yields and with good enantioselectivities. This iodide/ROOH catalytic system features a one-step synthesis… read more here.
Keywords: cinchona alkaloid; enantioselective oxidative; oxidative amination; alkaloid derived ... See more keywords
Flavopereirine—An Alkaloid Derived from Geissospermum vellosii—Presents Leishmanicidal Activity In Vitro
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DOI: 10.3390/molecules24040785
Abstract: Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs, low efficacy of alternative treatments, and resistance of the parasite. This work assesses the in vitro activity of flavopereirine on… read more here.
Keywords: flavopereirine; alkaloid derived; flavopereirine alkaloid; derived geissospermum ... See more keywords