Concise Syntheses of Lycojapomine Alkaloids Enabled by Radical Dearomatization of a Pyrrole.
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DOI: 10.1021/jacs.5c05721
Abstract: We disclose the first total syntheses of the complex alkaloids Lycojapomine A and B. Our synthetic strategy is built on a dearomatization and stepwise functionalization of a pyrrole starting material, constructing the three-dimensional structure of… read more here.
Keywords: dearomatization; lycojapomine alkaloids; concise syntheses; alkaloids enabled ... See more keywords