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Spirooxindol‐1,3‐oxazine Alkaloids: Highly Potent and Selective Antitumor Agents Evolved from Iterative Structure Optimization

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Published in 2022 at "Chemmedchem"

DOI: 10.1002/cmdc.202200162

Abstract: Spirooxindole‐1,3‐oxazines are a small and structurally unique class of spirooxindole alkaloids. To date, only four of these compounds have been isolated from natural sources, and their biological properties remained unknown thus far. Dioxyreserpine is a… read more here.

Keywords: highly potent; oxazine alkaloids; spirooxindol oxazine; alkaloids highly ... See more keywords