TP53 gene status is a critical determinant of phenotypes induced by ALKBH3 knockdown in non-small cell lung cancers.
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DOI: 10.1016/j.bbrc.2017.05.024
Abstract: Human AlkB homolog 3 (ALKBH3) is overexpressed in non-small cell lung cancers (NSCLC) and its high expression is significantly correlated with poor prognosis. While ALKBH3 knockdown induces apoptosis in NSCLC cells, the underlying anti-apoptotic mechanisms… read more here.
Keywords: gene status; alkbh3 knockdown; tp53 gene; induced alkbh3 ... See more keywords