Pd-Catalyzed C-H Functionalization of Indole-Containing Alkene-Tethered Aryl Halides with Alkynes To Construct Indole Alkaloid Scaffolds.
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DOI: 10.1021/acs.orglett.2c00882
Abstract: A convenient and straightforward approach for the construction of indole alkaloid scaffolds from indole-containing alkene-tethered aryl halides and alkynes through a sequential C-H activation, five-membered palladacycle formation, and alkyne insertion process has been described. The… read more here.
Keywords: indole alkaloid; containing alkene; indole; alkene tethered ... See more keywords
Palladium-Catalyzed Carbonylative Synthesis of Amide-Containing Indolo[2,1-a]isoquinolines from Alkene-Tethered Indoles and Nitroarenes.
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DOI: 10.1021/acs.orglett.2c04363
Abstract: In this new procedure, amide-containing indolo[2,1-a]isoquinoline scaffolds were prepared by palladium-catalyzed carbonylative cyclization of alkene-tethered indoles with nitroarenes. By using Mo(CO)6 as the CO source and reductant and nitroarenes as the nitrogen source, this reaction… read more here.
Keywords: containing indolo; catalyzed carbonylative; amide containing; palladium catalyzed ... See more keywords