Copper-Catalyzed Aminoarylation of Alkenes via Aminyl Radical Addition and Aryl Migration.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03973
Abstract: We describe a new strategy for aminoarylation of alkenes by copper-catalyzed smiles rearrangement using O-benzoylhydroxylamines as the amine reagent. This method affords various β-amino amide derivatives possessing a quaternary carbon center with wide functional group… read more here.
Keywords: copper catalyzed; alkenes via; catalyzed aminoarylation; aminyl radical ... See more keywords
1,2-Diamination of Alkenes via 1,3-Dipolar Cycloaddition with Azidium Ions or Azides.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03908
Abstract: We describe two new methods for the 1,2-diamination of alkenes. First, either an azidium ion (ArN═N+═NAr) undergoes 1,3-dipolar cycloaddition with an alkene to give a 1,2,3-triazolinium ion directly, or an intramolecular azide-alkene cycloaddition followed by… read more here.
Keywords: dipolar cycloaddition; azidium; via dipolar; diamination alkenes ... See more keywords
Iminoacylation of Alkenes via Photoredox N-Heterocyclic Carbene Catalysis.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00006
Abstract: The iminoacylation of alkenes via photoredox N-heterocyclic carbene catalysis is developed with the employment of alkene-tethered α-imino-oxy acids and acyl imidazoles. The corresponding substituted 3,4-dihydro-2H-pyrroles were afforded in moderate to good yields with good to… read more here.
Keywords: catalysis; via photoredox; iminoacylation alkenes; photoredox heterocyclic ... See more keywords
Hydrotrifluoroacetylation of Alkenes via Designer Masked Acyl Reagents.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c04294
Abstract: Because of its impressive ability to promote pharmaceutical activity, the introduction of trifluoromethylacyl (CF3CO) functionality into organic compounds has become an important and growing research area. Although various protocols have been developed to access trifluoroketones,… read more here.
Keywords: designer masked; via designer; alkenes via; hydrotrifluoroacetylation alkenes ... See more keywords
Visible light-induced aryltrifluoromethylation of hydroxy alkenes via radical trifluoromethylation-triggered aryl and heteroaryl migration
Sign Up to like & getrecommendations! Published in 2018 at "Organic chemistry frontiers"
DOI: 10.1039/c8qo00430g
Abstract: An efficient protocol was developed to achieve the aryltrifluoroalkylation of hydroxy alkenes via radical trifluoromethylation-triggered aryl migration. This method possesses several interesting features: (I) visible light is used as the sole promoter; (II) a new… read more here.
Keywords: hydroxy alkenes; alkenes via; radical trifluoromethylation; migration ... See more keywords
Perfluoroalkylative pyridylation of alkenes via 4-cyanopyridine-boryl radicals
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Science"
DOI: 10.1039/c8sc05237a
Abstract: A metal- and photo-free method for the perfluoroalkylative pyridylation of alkenes has been developed. read more here.
Keywords: cyanopyridine boryl; perfluoroalkylative pyridylation; alkenes via; via cyanopyridine ... See more keywords