Nickel-Catalyzed 1,2-Diarylation of Simple Alkenyl Amides.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b11942
Abstract: A nickel-catalyzed conjunctive cross-coupling of simple alkenyl amides with aryl iodides and aryl boronic esters is reported. The reaction is enabled by an electron-deficient olefin (EDO) ligand, dimethyl fumarate, and delivers the desired 1,2-diarylated products… read more here.
Keywords: alkenyl amides; catalyzed diarylation; diarylation simple; simple alkenyl ... See more keywords
A three-component difunctionalization of N-alkenyl amides via organophotoredox radical-polar crossover.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04101d
Abstract: Herein, we report a three-component organophotoredox coupling of N-alkenyl amides with α-bromocarbonyls and various nucleophiles. This transition metal-free difunctionalization protocol installs sequential C-C and C-Y (Y = S/O/N) bonds in alkenes. This reaction works with… read more here.
Keywords: amides via; difunctionalization; polar crossover; alkenyl amides ... See more keywords