Selective Conversion of Furoic Acid Derivatives to Multi‐Substituted Furanacrylate by a Ruthenium Catalyst
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DOI: 10.1002/cctc.201901365
Abstract: Furanacrylate derivatives, as a class of multi‐substituted furan compounds, have been widely used in drug synthesis, organic functional materials, novel polymer monomers, etc. In this paper, direct alkenylation and decarboxylation‐alkenylation of furoic acid derivatives to… read more here.
Keywords: alkenylation; furoic acid; multi substituted; acid derivatives ... See more keywords
Palladium/Carboxylic Acid‐catalyzed Alkenylation of Furfural and its Derivatives Using Alkynes
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DOI: 10.1002/cctc.202001685
Abstract: Furfural and its derivatives underwent alkenylation with alkynes via α‐C−H activation in the presence of a palladium/carboxylic acid catalyst to give the corresponding single and double alkenylated products. The reactive aldehyde group remained intact during… read more here.
Keywords: carboxylic acid; acid catalyzed; furfural derivatives; palladium carboxylic ... See more keywords
Advances in Rhodium-Catalyzed Oxidative Arene Alkenylation.
Sign Up to like & getrecommendations! Published in 2020 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.0c00036
Abstract: ConspectusAlkyl and alkenyl arenes are of substantial value in both large-scale and fine chemical processes. Billions of pounds of alkyl and alkenyl arenes are produced annually. Historically, the dominant method for synthesis of alkyl arenes… read more here.
Keywords: metal; alkenyl arenes; alkenylation; arene alkenylation ... See more keywords
Rhodium-Catalyzed Highly Enantio- and Diastereoselective Alkenylation of β,γ-Unsaturated Butenolides via Dynamic Kinetic Resolution.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03551
Abstract: A rhodium-catalyzed highly enantio- and diastereoselective alkenylation of β,γ-unsaturated butenolides is reported. The use of a chiral diene ligand, (S,S)-Ph-bod, enables the facile synthesis of chiral butyrolactones in high yields with extremely high enantioselectivities (>99%… read more here.
Keywords: alkenylation; enantio diastereoselective; rhodium catalyzed; unsaturated butenolides ... See more keywords
Ru(II)-Catalyzed C-H Alkenylation of Benzimidates with Unactivated Olefins: A Route to ortho-Alkenylated Benzonitriles.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04036
Abstract: A Ru(II)-catalyzed C-H alkenylation of benzimidates with unactivated alkenes providing ortho-alkenylated benzonitriles in good to excellent yields in a highly regio- and stereoselective manner is described. In the reaction, an imidate group converted into a… read more here.
Keywords: alkenylation benzimidates; alkenylation; catalyzed alkenylation; reaction ... See more keywords
Enamines as Surrogates of Alkene Carbanions for the Reductive Alkenylation of Secondary Amides: An Approach to Allylamines.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03943
Abstract: A new strategy to construct allylamines through reductive alkenylation of secondary amides with enamines is reported. The method features the use of trifluoromethanesulfonic anhydride as an activation reagent of amides, and enamines as unconventional alkenylation… read more here.
Keywords: reductive alkenylation; alkenylation secondary; secondary amides; surrogates alkene ... See more keywords
Rhenium-Catalyzed Regioselective ortho-Alkenylation and [3 + 2 + 1] Cycloaddition of Phenols with Internal Alkynes.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b01214
Abstract: An operationally simple and direct rhenium-catalyzed ortho-alkenylation ( C-alkenylation) of unprotected phenols with alkynes was developed. The protocol provided ortho-alkenylphenols exclusively, and formation of para- or multiply alkenylated phenols and hydrophenoxylation ( O-alkenylation) products were… read more here.
Keywords: ortho alkenylation; cycloaddition phenols; rhenium catalyzed; catalyzed regioselective ... See more keywords
Hydride–Rhodium(III)-N-Heterocyclic Carbene Catalyst for Tandem Alkylation/Alkenylation via C–H Activation
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DOI: 10.1021/acscatal.9b01233
Abstract: The unsaturated hydride complex RhClH{κ2-N,C-(C11H8N)}(IPr) {IPr = 1,3-bis-(2,6-diisopropylphenyl)imidazolin-2-carbene} (2) has been prepared via C–H activation of 2-phenylpyridine and fully characterized by spectroscopic methods and X-ray diffraction analysis. Complex 2 efficiently catalyzes the isomerization of terminal… read more here.
Keywords: hydride; alkylation alkenylation; tandem alkylation; alkylation ... See more keywords
The underlying factors controlling the Pd-catalyzed site-selective alkenylation of aliphatic amines.
Sign Up to like & getrecommendations! Published in 2017 at "Dalton transactions"
DOI: 10.1039/c7dt01568b
Abstract: The Pd(ii)-catalyzed site-selective δ-C(sp3)-H alkenylation in the presence of more accessible γ-C(sp3)-H bonds is investigated by DFT calculations. Migratory insertion is found to be both the rate-limiting and the selectivity-determining step. The origin of the… read more here.
Keywords: factors controlling; site selective; underlying factors; catalyzed site ... See more keywords
Pd-catalysed, Ag-assisted C2-H alkenylation of benzophospholes.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04942b
Abstract: A palladium-catalysed, silver-assisted regioselective C2-H alkenylation of benzophospholes with terminal alkenes has been developed. The palladium catalysis accommodates styrenes and electron-deficient alkenes including ester, ketone, nitrile, and phosphonate. Thus, this protocol enables the rapid construction… read more here.
Keywords: alkenylation; assisted alkenylation; alkenylation benzophospholes; catalysed assisted ... See more keywords
Late-stage ortho-C–H alkenylation of 2-arylindazoles in aqueous medium by Manganese(i)-catalysis
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DOI: 10.1039/d2ra03547b
Abstract: Earth-abundant and water-tolerant manganese(i) catalyzed alkenylation of 2-arylindazole with alkyl and aryl alkynes through C–H bond activation is described with a unique level of E-selectivity. The reaction proceeds through the control of C3 nucleophilicity of… read more here.
Keywords: alkenylation arylindazoles; stage ortho; ortho alkenylation; alkenylation ... See more keywords