The direct C–H alkenylation of quinoline N-oxides as a suitable strategy for the synthesis of promising antiparasitic drugs
Sign Up to like & getrecommendations! Published in 2020 at "New Journal of Chemistry"
DOI: 10.1039/c9nj05054j
Abstract: Functionalized quinolines are an important group of heterocyclic molecules with diverse, different, and interesting biological and pharmacological activities. Traditionally, several methods have been developed for the construction of this N-heterocyclic ring, but nowadays the functionalization… read more here.
Keywords: quinoline oxides; chemistry; direct alkenylation; alkenylation quinoline ... See more keywords
Zinc-catalyzed C-H alkenylation of quinoline N-oxides with ynones: a new strategy towards quinoline-enol scaffolds.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc00245g
Abstract: A zinc-catalyzed C-H alkenylation of quinoline N-oxides with ynones has been developed to rapidly assemble a broad collection of valuable quinoline-enol organic architectures. Uncommonly, this novel reaction involves C-H functionalization, and N-O, C-C and C[triple… read more here.
Keywords: quinoline oxides; quinoline; zinc catalyzed; catalyzed alkenylation ... See more keywords