Diastereoselective Substitution Reactions of Acyclic β-Alkoxy Acetals via Electrostatically Stabilized Oxocarbenium Ion Intermediates.
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DOI: 10.1021/acs.orglett.2c01004
Abstract: Substitution reactions of acyclic β-alkoxy acetals proceeded with generally high diastereoselectivities (>90:10) to form the anti product. Mechanistic experiments supplemented with computational studies suggest that, upon activation of the acetal, the resulting oxocarbenium ion is… read more here.
Keywords: oxocarbenium ion; reactions acyclic; electrostatically stabilized; acyclic alkoxy ... See more keywords