ZnBr2-Mediated Cascade Reaction of o-Alkoxy Alkynols: Synthesis of Indeno[1,2-c]chromenes.
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DOI: 10.1021/acs.orglett.6b03642
Abstract: A Lewis acid-mediated cascade annulation of o-alkoxy alkynols in the presence of ZnBr2 has been developed. The cascade cyclization proceeds through a 5-exo-dig cyclization followed by a Friedel-Crafts reaction and ring-opening sequence to synthesize indeno[1,2-c]chromenes.… read more here.
Keywords: indeno chromenes; alkoxy alkynols; znbr2 mediated; reaction ... See more keywords