Rhodium-Catalyzed O-H Insertion Reactions to (2-Diazo-1,1,3,3,3-pentafluoropropyl)phosphonate: A Convenient Route to Fluorinated β-Alkoxy Vinylphosphonates.
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DOI: 10.1021/acs.orglett.5c04281
Abstract: The rhodium(II)-catalyzed insertion of benzyl and alkyl alcohols with 2-diazo-1,1,3,3,3-pentafluoropropylphosphonate unexpectedly afforded fluorinated β-alkoxy vinylphosphonates. The reaction proceeds under mild conditions and shows broad substrate scope. Twenty-four new derivatives were synthesized in moderate to excellent… read more here.
Keywords: phosphonate; catalyzed insertion; rhodium catalyzed; alkoxy vinylphosphonates ... See more keywords