Photodynamic therapy for ras-driven cancers: targeting G-quadruplex RNA structures with bifunctional alkyl-modified porphyrins.
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DOI: 10.1021/acs.jmedchem.9b01577
Abstract: Designing small molecules capable to break down G4 structures in mRNA (RG4s) offers an interesting approach to cancer therapy. Here, we have studied cationic porphyrins (CPs) bearing an alkyl chain up to 12 carbons, as… read more here.
Keywords: photodynamic therapy; alkyl cps; therapy; therapy ras ... See more keywords