Bis(pinacolato)diboron‐Enabled Ni‐Catalyzed Reductive Arylation/Vinylation of Alkyl Electrophiles
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DOI: 10.1002/advs.202404301
Abstract: Herein, the use of economically and environmentally friendly bis(pinacolato)diboron (B2Pin2) is described as a non‐metallic reductant in mediating Ni‐catalyzed C(sp3)–C(sp2) reductive cross‐coupling of alkyl electrophiles with aryl/vinyl halides. This method exhibits excellent suitability for heteroaryl… read more here.
Keywords: enabled catalyzed; diboron enabled; alkyl electrophiles; pinacolato diboron ... See more keywords
Nickel-Catalyzed Reductive Alkene Cross-Dialkylation with Unactivated Alkyl Electrophiles.
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DOI: 10.1021/acs.orglett.3c04207
Abstract: A Ni-catalyzed reductive dialkylation of 8-aminoquinoline-tethered aliphatic alkenes with two unactivated alkyl electrophiles is disclosed here. Key to the development of this transformation is the combination of primary alkyl (pseudo)halides and secondary alkyl iodides that… read more here.
Keywords: unactivated alkyl; alkyl electrophiles; dialkylation; reductive alkene ... See more keywords
C-C and C-X coupling reactions of unactivated alkyl electrophiles using copper catalysis.
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DOI: 10.1039/d0cs00316f
Abstract: Transition metal-catalysed cross-coupling reactions are widely used for construction of carbon-carbon and carbon-heteroatom bonds. However, compared to aryl or alkenyl electrophiles, the cross-coupling of unactivated alkyl electrophiles containing β hydrogens remains a challenge. Over the… read more here.
Keywords: unactivated alkyl; reactions unactivated; copper; alkyl electrophiles ... See more keywords