Differentiation of Sialyl Linkages Using a Combination of Alkyl Esterification and Phenylhydrazine Derivatization: Application for N-Glycan Profiling in the Sera of Patients with Lung Cancer.
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DOI: 10.1021/acs.analchem.2c00105
Abstract: Alterations in oligosaccharides and types of sialic acid (SA) attachments have been associated with different pathological states. Matrix-assisted laser desorption mass spectrometry (MS) is commonly used for glycosylation studies. However, native sialylated glycans are suppressed… read more here.
Keywords: lung cancer; alkyl esterification; glycan profiling; profiling sera ... See more keywords