Effect of the alkyl group in the piperazine N-substitution on the therapeutic action of rifamycins: A drug-membrane interaction study.
Sign Up to like & getrecommendations! Published in 2018 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.04.027
Abstract: In this work, we studied the effects of the N-alkyl group (methyl, cyclopentyl) in the piperazine ring of, respectively, rifampicin (RIF) and rifapentine (RPT) to correlate this substitution with their differential pharmacokinetic properties and overall… read more here.
Keywords: alkyl group; group; drug membrane; interaction ... See more keywords
Reversible Alkyl-Group Migration between Iron and Sulfur in [Fe4S4] Clusters.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c03195
Abstract: Synthetic [Fe4S4] clusters with Fe-R groups (R = alkyl/benzyl) are shown to release organic radicals on an [Fe4S4]3+-R/[Fe4S4]2+ redox couple, the same that has been proposed for a radical-generating intermediate in the superfamily of radical… read more here.
Keywords: fe4s4 clusters; group; group migration; alkyl group ... See more keywords
Preparation of New Sargassum fusiforme Polysaccharide Long-Chain Alkyl Group Nanomicelles and Their Antiviral Properties against ALV-J
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26113265
Abstract: Avian leukosis virus subgroup J (ALV-J) is an immunosuppressive virus which has caused heavy losses to the poultry breeding industry. Currently, there is no effective medicine to treat this virus. In our previous experiments, the… read more here.
Keywords: alkyl group; long chain; chain alkyl; fusiforme polysaccharide ... See more keywords