Alkyl-guanidine Compounds as Potent Broad-Spectrum Antibacterial Agents: Chemical Library Extension and Biological Characterization.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b00619
Abstract: Nowadays, the increasing of multidrug-resistant pathogenic bacteria represents a serious threat to public health, and the lack of new antibiotics is becoming a global emergency. Therefore, research in antibacterial fields is urgently needed to expand… read more here.
Keywords: broad spectrum; alkyl guanidine; compounds potent; guanidine compounds ... See more keywords
Identification, synthesis and biological activity of alkyl-guanidine oligomers as potent antibacterial agents
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-08749-6
Abstract: In the last two decades, the repertoire of clinically effective antibacterials is shrinking due to the rapidly increasing of multi-drug-resistant pathogenic bacteria. New chemical classes with innovative mode of action are required to prevent a… read more here.
Keywords: biological activity; alkyl guanidine; activity alkyl; synthesis biological ... See more keywords