Synthesis of 2-Cyanomethyl Indane Derivatives via Pd-Catalyzed Alkene Difunctionalization Reactions of Alkyl Nitriles.
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DOI: 10.1021/acs.orglett.3c00571
Abstract: The synthesis of indanes bearing substituted cyanomethyl groups at C2 is achieved through Pd-catalyzed coupling reactions between 2-allylphenyl triflate derivatives and alkyl nitriles. Related partially saturated analogues were generated from analogous transformations of alkenyl triflates.… read more here.
Keywords: cyanomethyl indane; alkyl nitriles; synthesis cyanomethyl; via catalyzed ... See more keywords