Electrochemical synthesis of 2-alkyl-4-phenylalkan-2-ols via cathodic reductive coupling of alkynes with unactivated aliphatic ketones.
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DOI: 10.1039/d2cc06819b
Abstract: Herein, we present an efficient electrochemical method for synthesizing 2-alkyl-4-phenylalkan-2-ols through an electrochemically driven cathodic reductive coupling of the terminal and internal acetylenes with unactivated aliphatic ketones under mild conditions. The process proceeds through a… read more here.
Keywords: aliphatic ketones; reductive coupling; cathodic reductive; unactivated aliphatic ... See more keywords