Synthesis of di- and trihydroxy proline derivatives from D-glycals: Application in the synthesis of polysubstituted pyrrolizidines and bioactive 1C-aryl/alkyl pyrrolidines.
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DOI: 10.1016/j.carres.2019.02.004
Abstract: Six different types of O-benzyl protected proline derivatives have been synthesized from D-glycals and 2C-formyl-glycals. One of the di-O-benzyl protected proline derivatives has been utilized for the synthesis of polysubstituted pyrrolizidines via [3 + 2] cycloaddition in… read more here.
Keywords: synthesis polysubstituted; synthesis; proline derivatives; aryl alkyl ... See more keywords