N-Heterocyclic carbene copper-catalyzed direct alkylation of terminal alkynes with non-activated alkyl triflates.
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DOI: 10.1039/c7cc00891k
Abstract: (NHC)-Cu-catalyzed C(sp)-C(sp3) bond formation has been successfully achieved under mild conditions. Nonactivated alkyl triflates, which could be easily derived from alcohols, were utilized as C-O electrophiles. Mechanistic studies suggested that copper acetylide was the active… read more here.
Keywords: carbene copper; alkyl triflates; copper; catalyzed direct ... See more keywords