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Published in 2018 at "Synlett"
DOI: 10.1055/s-0036-1591581
Abstract: An efficient Pd(0)-catalyzed alkylarylation of N-alkyl-N-methacryloylbenzamides with alkyl iodides for the synthesis of isoquinoline-1,3-diones is described. A highlight of the method is its excellent functional-group tolerance. Mechanistic investigations suggest that a radical addition/cyclization process is…
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Keywords:
alkylarylation alkyl;
catalyzed alkylarylation;
alkyl iodides;
methacryloylbenzamides alkyl ... See more keywords