Oxy-Alkylation of Allylamines with Unactivated Alkyl Bromides and CO2 via Visible-Light-Driven Palladium Catalysis.
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DOI: 10.1021/acs.orglett.8b01079
Abstract: A selective oxy-alkylation of allylamines with unactivated alkyl bromides and CO2 via visible-light-driven palladium catalysis is reported. The commercially available Pd(PPh3)4 is used as the sole catalyst in this three-component reaction. A variety of tertiary,… read more here.
Keywords: unactivated alkyl; allylamines unactivated; bromides co2; alkylation allylamines ... See more keywords
Palladium(II)-Catalyzed Stereospecific Alkenyl C–H Bond Alkylation of Allylamines with Alkyl Iodides
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DOI: 10.1021/acscatal.8b04415
Abstract: A palladium-catalyzed stereospecific alkylation of allylamines with primary and secondary alkyl iodides is described. Isoquinoline-1-carboxamide (IQA) acts as directing group to generate multisubstituted olefin products in cis configuration in moderate to good yields. Mechanistic studies… read more here.
Keywords: alkenyl bond; catalyzed stereospecific; palladium catalyzed; alkylation allylamines ... See more keywords