Photocatalytic cascade alkylation/cyclization of N‐arylacrylamides with simple alkanes: a convenient approach to quaternary C3 alkylated oxindoles
Sign Up to like & getrecommendations! Published in 2024 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202400554
Abstract: A convenient and efficient protocol for the synthesis of 3,3‐dialkylated oxindoles through photocatalytic aerobic radical‐cascade alkylation/cyclization of N‐arylacrylamides with the alkyl radicals generated from simple alkanes is described. This method features a broad substrate scope,… read more here.
Keywords: cyclization arylacrylamides; simple alkanes; alkylation cyclization; cascade alkylation ... See more keywords
Dinuclear zinc-catalyzed asymmetric Friedel-Crafts alkylation/cyclization of 3-aminophenols with α,α-dicyanoolefins.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc04177k
Abstract: An enantioselective Friedel-Crafts alkylation/cyclization tandem reaction of 3-aminophenols with α,α-dicyanoolefins has been performed successfully using a chiral dinuclear zinc catalyst, leading to a range of chiral 2-amino-4H-chromenes (up to 98% yield and >99% ee). To… read more here.
Keywords: crafts alkylation; aminophenols dicyanoolefins; dinuclear zinc; zinc ... See more keywords