Zinc-Mediated Decarboxylative Alkylation of Gem-difluoroalkenes.
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DOI: 10.1021/acs.orglett.8b01866
Abstract: An efficient and mild zinc-mediated decarboxylative alkylation of gem-difluoroalkenes with N-hydroxyphthalimide (NHP) esters, to give monofluoroalkenes in moderate to excellent yields with high Z-selectivity is reported. The reaction tolerates a broad range of functional groups… read more here.
Keywords: mediated decarboxylative; decarboxylative alkylation; gem difluoroalkenes; alkylation gem ... See more keywords